ABSTRACT
Objective To research the significance of detection of cholyglycine(CG) and total bile acid (TBA ) in intrahepatic cholestasis of pregnancy(ICP) .Methods Totally 85 gestational patients of ICP and 85 normal pregnancy pregnant women(control group) were chosen .Indexes including CG ,TBA ,ALT ,AST and TBIL were detected ,and the results were compared .Results In ICP group ,the levels of serum CG ,TBA ,ALT ,AST and TBIL were significantly higher than those in the normal control group ,and the differences were statistically significant(P< 0 .05) ;The positive rates of serum CG and TBA in ICP were significant higher than those in control group(P< 0 .05) .Conclusion The level of CG and TBA in intrahepatie cholestasis of pregnancy are significantly increased and might be sensitive indicators of gestaional diabetes in intrahepatie cholestasis of pregnancy ,the joint detection is of great clinical significance for ICP early diagnosis and monitoring .
ABSTRACT
Objective To investigate standard diagnosis and treatment of cerebrospinal fluid (CSF) leakage to improve the prognosis of the patients. Methods A retrospective study was done on 75 patients with CSF leakage from January 2004 to March 2007 in our hospital. There were 51 patients with rhinorrhea, nine with otorrhea and 15 with wound/incision leakage. Of all, 39 patients had traumatic leakage, 32 postoperative leakage and four spontaneous leakage. In the study, 23 patients were cured by position testing and drug therapy and 16 by cerebrospinal fluid drainage and/or wound debridement but 36 were treated with surgeries including craniotomy repair in 17, extracranial repair in 17 and CSF shunt in five (three received CSF shunt after repair). Results Of all, 64 patients were cured, 10 gained im-provement but one died. Conclusion Standard diagnosis and treatment of CSF leakage helps improve cure rate and reduce complications.